US annual cost for four VPDs $26.5 billion (2013)

Research published in 2015 in the Journal of Primary Prevention has estimated the cost of four of the most significant vaccine preventable diseases. (Estimated Human and Economic Burden of Four Major Adult Vaccine-Preventable Diseases in the United States, 2013). The researcch explores the economic and human cost of  (1) influenza, (2) pneumococcal disease (both invasive disease and pneumonia), (3) herpes zoster (shingles), and (4) pertussis (whooping cough).

The research estimates the annual US cost for the four adult VPDs as being $26.5 billion.